Loftus began acting aged nine at the Carlton Workshops, and later took her A-Levels at the Becket School in Nottingham. She played several small roles in television dramas and films, including This Is England.
Loftus made her mainstream television debut in 2000 aged 10 when she appeared in an episode of Peak Practice. Subsequently, Loftus has appeared in various television series, including Casualty, Doctors, The Bill (2008), and in theITV comedy drama The Fattest Man in Britain starring Timothy Spall and Bobby Ball
In 2008 Loftus was described as a 'Star of Tomorrow' in Screen International magazine. She also appeared in Daniel Elliott’s short Jade, which won a Silver Bear at the Berlin International Film Festival in 2009.
In 2010 Loftus starred in the BBC drama Five Daughters, as murder victim Gemma Adams. In July of the same year she took the leading female role in another BBC drama, Dive, by BAFTA award winning Dominic Savage and Simon Stevens, in a cast that included Skins actor Jack O'Connell, Eddie Marsan, Gina Mckee, Joseph Mawle and Ewen Bremner. Dive was critically acclaimed, Euan Ferguson of The Observer predicting that Aisling "Ash" Loftus will be a "phenomenon".
Loftus played Leonie Fowler in the summer box office hit Spur of the Moment by Anya Reiss at the Royal Court Theatre in 2010 in London where she has received favourable reviews with Dominic Cavendish of the Telegraph calling her"superb"'
In 2011 Loftus starred in a new BBC TV film version of The Borrowers broadcast on Boxing Day, as Arrietty. This was followed up in 2012 with roles in 2 BBC series : Jade in Public Enemies & Cassandra in Good Cop and in 2013 by the role of Agnes Towler in Mr Selfridge.
|2013||Mr Selfridge||Agnes Towler||ITV||All episodes|
|2012||Public Enemies||Jade||BBC||2 episodes|
|2011||Death of a Superhero||Shelly||Grand Pictures|
|2011||The Borrowers||Arrietty Clock||BBC|
|2011||Page Eight||Melissa Legge||BBC|
|2011||Case Histories||Lily Rose/ Tanya||BBC||2 episodes|
|2010||Oranges and Sunshine||Susie||Jim Loach's first feature film|
|2010||Thorne: Sleepyhead||Rachel||Sky||3 part drama|
|2010||Dive||Lindsey||BBC||2 part drama|
|2010||Five Daughters||Gemma Adams||BBC||2 episodes|
|2009||The Fattest Man in Britain||Amy||ITV||one off drama|
|2009||Jade||Jade||Daniel Elliot short film||won Silver Bear at the Berlin International Film Festival|
|2008||The Bill||Sophie Randall||ITV||2 episodes|
|2008||Doctors||Ellie Lowell||BBC||1 episodes|
|2008||Casualty||Jo Balmayne||BBC||1 episode|
|2006||This Is England||Shane Meadows film||part was cut from the theatrical release|
|2006||Casualty||Mellie Bennett||BBC||1 episodes|
|2006||Blind Man's Alley||Player 4||Tony Kelly short film|
|2005||Doctors||Emma Tyler||BBC||1 episode|
|2004||Help! I'm A Teenage Outlaw||Montague's Food Tester||1 episode|
|2001||A Fish Out of Water||Angela||BBC|
|The Worst Witch||ITV|
|2000||Peak Practice||Abby Moffett||ITV||1 episode|
|2011||Noises Off by Michael Frayn||Poppy||Old Vic Theatre|
|2010||Spur of the Moment by Anya Reiss||Leonie Fowler||Royal Court Theatre|
|We Happy Few by Imogen Stubbs||Nottingham Playhouse|
|He's Talking, Just, The Spider Men||various||National Theatre Connections||National Theatre, Castle Theatre, Wellingborough, Nottingham Playhouse|