Powell began her career in 1986 presenting the BBC2 music programme No Limits  and then moved to Saturday morning television for children, first co-presenting UP2U for BBC1 during the summers of 1988 and 1989, ITV's Ghost Train and then Gimme 5, again on ITV. She was also a presenter of Top of the Pops in 1989. In the mid-1990s, she became the hostess on ITV's version of Wheel of Fortune.
More recently, she has presented Soap Fever, Live Talk, Getaway and Our House for UKTV Style. She tried to make it as a stand-up comedienne in Granada Television's Stand Up Jenny, and was a regular on ITV'sLoose Women. In 2005, she was one of the competitors in the ITV reality TV show Celebrity Wrestling, competing under the name The Avenger.
In 1997 she appeared on Channel 4's Brass Eye, a satirical spoof documentary show produced by Chris Morris. She talked earnestly about the perils of 'heavy electricity' and warned that the South of England could be catapulted towards Finland if people did not bang on wires with hammers.
Also in the late 1990s she co-presented the programme 4 Wheels Good 2 Wheels Better for satellite TV station Granada Plus.
Powell married millionaire Toby Baxendale and they had two daughters, Constance and Pollyanna. In 2009 Powell announced she had split up with her husband. She lives with her daughters in Cheshire.