Mary Jo Deschanel (born November 25, 1945) is an American actress.
Deschanel was born as Mary Jo Weir. Her ancestry includes Irish, French, Swiss, Dutch, and English. In her first major appearance in show business in 1983, Deschanel played Annie Glenn, the wife of the astronaut John Glenn in the movie adaptation of the Tom Wolfe book, The Right Stuff.
The next year after acting in The Right Stuff, Deschanel played Betty Fernandez, the remarried former wife of the astronaut Dave Bowman (played by Keir Dullea), in the film 2010: The Year We Make Contact.
Deschanel played Eileen in the TV series Twin Peaks. She has appeared in the TV series House in the episode "Simple Explanation" as Julia Kutner, the adoptive mother of recently deceased Dr. Lawrence Kutner.
Deschanel was featured a second time as the wife of Ed Harris' character in the movie Winter Passing, although she was only seen in a photograph on the wall. In spite of never physically appearing in this movie, she did receive full billing in the credits as the character "Mary".