Lombard was born in London. She is half Spanish and half Italian. Her TV credits include regular roles in Love Soup and Roman's Empire but she is most famous for her role as WPC Shaz Granger in the hit BBC Drama Ashes to Ashes alongside Phillip Glenister and Keeley Hawes.
Other credits include guest roles in Doctors, Twisted Tales, Nathan Barley, Murder in Suburbia ("Witches", as a school girl named Myra who, among other things, bakes brownies and attempts to seduce her music teacher dressed in lacy underwear), a lead role in St Trinian's 2: The Legend of Fritton's Gold, Midsomer Murders:A Picture of Innocence, and a part in the feature-length ITV drama Tunnel Of Love, alongside Jack Dee. Lombard has also played Lavya in the episodes "Hello Queppu" and "Artefact" of the BBC2 sci-fi comedy series Hyperdrive, and Stevie in the fourth episode of the BBC2 comedy Saxondale. She appeared as Lady Anne in the radio four comedy The Castle.
Lombard has also appeared in several stage productions, including People Who Don't Do Dinner Parties, alongside Mark Stobbart. She also featured in an advert for the MINT Credit Card, where her "boyfriend" sneezed over her parents.
Lombard played June in the short film Vanilla Song, created by National Film and Television School students, as well as Ian Sciacaluga’s short film noir Imbroglio.She played The Muse in William Mager's 2008 short film Stiletto, funded by Apex Arts and the Hitchcock Production Fund.
She had a small role in Terry Gilliam's film The Imaginarium of Doctor Parnassus, playing a friend of the character Sally. In 2009, she worked on the film St. Trinian's II: The Legend of Fritton's Gold, playing Zoe, the leading 'Emo'.
She most recently played Maria, key witness of Pope Alexander's lechery for the conspiring cardinals, in the premiere episode of the 2011 TV series, The Borgias.
She also voiced the role of Mirania in the 2011-2012 game The Last Story for the Nintendo Wii .